Rich VanKonynen,PhD who is responsible for the development of a simplified methylation protocol (a relatively new treatment that came out in the past two years or so) for CFIDS thinks the following article represents a major breakthrough in understanding CFIDS.
Dr. Sarah Myhill and coauthors have just published a paper on
mitochondrial dysfunction in CFS. They found that there is mito
dysfunction in CFS, and that the degree of this dysfunction is
correlated with the degree of disability of people with CFIDS. A pdf of the paper
is available here free:
In Rich's opinion, this is a landmark development in CFS research. It
shows that the fatigue in CFS is traceable to problems in the basic
powerplants of the cells of the body. This should draw the attention
of the CFS research community to the fundamental biochemistry of
metabolism, and it should also be a powerful bulwark against the
wrongheaded view that CFS is a psychiatric disorder, which is
particularly dominant in the UK.
The next step is to figure out what is causing the mitochondria dysfunction and there are competing theories about this.
Luckily, the top CFIDS researchers in the field along with top LLMD's are meeting at least annually as part of the Sonoma Working Group to discuss issues like this.
I skimmed the paper and it just describes the problem. I have no understanding of biochemistry it doesn't make a lot of sense to me.
The only problem is how do you treat this???? It's kind of like saying "well we know the reason you are paralyzed is because your neck is broken."