Thursday, May 30, 2013

Experimenting

I'm not feeling well. At all.  This past week I've been indoors most of the time because of the weather. I wonder if that explains the recent emergence of new/old symptoms.

Monday I started getting the chills off and on but no fever. That night I had bad nightsweats. The chills have continued to today. While showering I was having chills!

I'm also having a lot of nausea which started suddenly yesterday and has persisted. Nausea, lightheadedness, feeling mildly off balance at times, and increase in POTS symptoms. I'm also have moderate muscle pain in most of my body.

Last night I had light, sound, smell sensitivity along with those lovely migraine like headaches.  I felt (and feel) like I have both the flu and a bad hangover.

I had an episode like this for one day after being at my sister's house for about 6 weeks.  It was tough and I worried I would be stuck like that. This episode isn't as bad (I couldn't look at a computer screen or the tv).

Today I have sheering pain in the muscles in the back of my legs as well as my lower back, and lower arms. It does not feel related to a disc issue.

I'm also having some shortness of breath at times.  Stuffy sinuses, dry gritty eyes, increase in fatigue.

For about 2 hours yesterday I had trouble staying upright. When the bad nausea started I headed out to the backyard thinking being outside would help. I had just been under the sink looking for a sponge. I believe the dishwasher has a mold problem (can smell it). The dishwasher is right next to the sink.

When I got outside the heat made me almost pass out. I had to sit until I felt confident I wouldn't pass out. As I started my journey upstairs to my bedroom I would take a few steps and have to sit down because of the lightheadedness and dizziness.

I emailed my doctor who suggested a biopsy for Small Nerve Fiber Disease. I looked it up and it looks like what my Dad has. Unfortunately I also have a majority of the symptoms. It has a genetic component.

I seemed to have developed heat intolerance also.

So I've been experimenting. I've taken note of my symptoms when I'm in my bedroom near the small amount of stuff left from the old water damaged/moldy apartment.

When I go outside I don't feel as bad. I come upstairs and start to develop symptoms.

How in the heck am I supposed to convince a doctor to do a biopsy when I can't even convince doctors around here that I have a real medical condition and need medical help NOT a referral to a psychiatrist.

Another link to small nerve fiber disease:

"Small fiber neuropathy has been associated with many medical conditions, including glucose dysmetabolism,3 connective tissue disease,4,5dysthyroidism,6 vitamin B12 deficiency, paraproteinemia, human immunodeficiency virus (HIV) infection,7 hepatitis C virus infection, celiac disease,8 restless legs syndrome,9 neurotoxic drug exposure, hereditary diseases, and paraneoplastic syndrome. While most of these conditions cause a length-dependent small fiber neuropathy, others (Sj√∂gren disease, celiac disease, and paraneoplastic syndrome) can cause a form of small fiber neuropathy that is not length-dependent.4,8,10"
Small nerve fiber neuropathies also may result in autonomic and enteric dysfunction. Patients often do not identify the relationship of these symptoms to their sensory complaints; however, when asked, they may report dry eyes, dry mouth, postural lightheadedness, presyncope, syncope, abnormal sweating, erectile dysfunction, nausea, vomiting, diarrhea, constipation, early satiety, difficulty with urinary frequency, nocturia, and/or voiding.

Interesting that neurotoxic drug exposure is listed as one of the causes. I wonder if neurotoxins produced by the mold can also cause this.

Toxin Induced Neuropathy:


Motor > Sensory Toxic Neuropathies:

1. dapsone 2. disulfiram 3. nitrofurantoin 4. organophosphates 5. lead 6. vincristine

Sensory > Motor Toxic Neuropathies:

1. cisplatin 2. pyridoxine 3. thalidomide 4. thallium 5. arsenic 6. polychlorinated biphenyls

Systemic Features Suggestive of Neurotoxic Disease

The neuropathies resulting from most neurotoxins are remarkably similar in both their clinical and electrophysiologic characteristics. Occasionally, there may be systemic complaints or signs which suggest the nature of the neurotoxic insult. Usually these symptoms/signs are apparent with either acute high-level, or chronic low-level intoxication. The following clinical characteristics may be the identifying feature that suggests a TxPN:

- acrylamide - dermal contact associated with contact dermatitis, excessive sweating of hands and feet.
- carbon disulfide - chronic low-level exposure associated with a variety of behavioral and psychiatric abnormalities along with peripheral neuropathy.
- ethyl oxide - cognitive impairment and neuropathy with prolonged low-level exposure.
- hexacarbons - acute, high-level exposure may mimic AIDP with prominent autonomic dysfunction.
- lead - Mee’s lines, blood abnormalities (basophilic stippling, anemia), GI abnormalities, and predominantly a motor neuropathy.
- mercury - tremor and ataxia with a predominantly sensory neuropathy.
- methyl bromide - corticospinal and cerebellar dysfunction along with an axonal neuropathy.
6- organophosphate intoxication - early cholinergic symptoms, may have intermediate syndrome preceding neuropathy, late emergence of corticospinal tract dysfunction as the peripheral neuropathy resolves.
- polychlorinated biphenyls - symmetric sensory neuropathy associated with brown acneiform skin eruption and brown pigmented nails.
- thallium - prominent GI distress with high-level exposure, alopecia, Mee’s lines, hyperkeratosis with more prolonged exposure, sensory greater than motor neuropathy.




1 comment:

  1. wow, thanks for posting this. It describes me exactly. I have never heard of it before though. Is there treatment for it? Hmmm ...

    ReplyDelete